Networks, connected. Information, activated. Care, coordinated.



600 EHR

95% OF




    7 out of 10 office-based physicians e-prescribed in 2013, a 4% change in e-prescribing use over 2012.

    Note: The darker the area, the greater the concentration of active e-prescribers







  • More than Half of All Prescriptions Routed Electronically2


    The Surescripts network routed more than one billion e-prescriptions in 2013, representing 58% of all eligible prescriptions. This shows a 32% increase in volume over 2012 and almost double the total in 2011.

    19% Continued Growth in Medication Histories Delivered


    Surescripts exchanged nearly 700 million Medication History transactions in 2013, up from nearly 400 million in 2011.

    Mail-Order Pharmacies Routed 31% More E-Prescriptions


    In 2013, Surescripts saw a 31% increase in the number of e-prescriptions routed to mail-order pharmacies. The volume of e-prescriptions routed to mail-order pharmacies has increased significantly in the past five years, from just below 4 million in 2009 to more than 63 million in 2013.









  • Pediatricians Lead Growth in E-Prescribing Adoption with 24% Increase

    Specialty e-prescribing in 2012 e-prescribing in 2013 year-to-year growth
    1. Internist 79% 96% +22%
    2. family practitioner 71% 85% +20%
    3. endocrinology & metabolism 71% 81% +14%
    4. cardiovascular disease 72% 80% +11%
    5. pediatrician 63% 78% +24%
  • Solo Practitioners Drive Growth in E-Prescribing Adoption

    GROWTH 2013
    2012 58%
    2013 69%
    2 TO 5
    2012 64%
    2013 73%
    6 TO 10
    2012 65%
    2013 73%
    11 TO 25
    2012 55%
    2013 61%
    26 TO 100
    2012 37%
    2013 42%
    2012 34%
    2013 38%
  • 95% of Pharmacies Adopted E-Prescribing

    Independent Pharmacies


    Adoption of e-prescribing by independent pharmacies changed 11% between 2011 and 2013.

    Chain Pharmacies


    Chain pharmacies remained constant at 98% adoption during the same period.


    In a typical metropolitan area with a population of 2 million, such as Cleveland, Ohio or Kansas City, Missouri, a web of providers and payers navigates a complex system to provide quality care to an increasingly informed and digitally connected patient.

    Read more
  • Transforming Health
    Information Exchange

    The complexity of the healthcare system multiplies with the added communications needs among nursing homes, retail clinics, and long-term care facilities or when a patient needs care while traveling outside their local community.

    Data is the life blood of healthcare, but the benefits of improving patient care, increasing efficiency and decreasing costs, cannot be realized if health information exists in isolation.

    Health information technology offers significant promise. The ability to share clinical information, quickly and securely, will transform the healthcare system. The electronic exchange of health information can help improve quality and control costs, but this simple idea is a difficult task given the complexity of the U.S. healthcare system.

    Surescripts has the infrastructure, data network, provider and supplier directories, and experience in developing standards to ensure that the healthcare system is connected and interoperable.






    Connecting healthcare is a monumental task, but real progress is occurring and the impact is tangible. Surescripts has been connecting, exchanging, and activating health information for over a decade, starting with e-prescribing and broadening across other areas of healthcare. Our experience is significant and our potential far-reaching.

    The vast majority of e-prescription data in America flows through our network, including prescription, medication history, formulary and benefits information. The range of information that we exchange is expanding and we continually develop services to help people identify and access it.

    Our Expanded Services Include:

    Medication History:
    Improving Patient Safety and Driving More Accountable Care Learn More

    Addressing Controlled Substance Fraud and Abuse Learn More

    Immunization Services:
    Driving More Coordinated Care Learn More

  • Medication History:

    Improving Patient Safety and Driving More Accountable Care

    Adverse drug interactions present significant risks to patient safety, especially in hospitals where a patient cannot communicate their medications because they are unconscious or in a compromised state. Surescripts provides access to a patient's comprehensive, real-time, electronic medication history, based on PBM claims and pharmacy fill data, prior to administering treatment. Electronic access to medication history improves patient safety and is leading the way to more accountable care by:

    • Reducing the risk of adverse drug events (ADEs) by increasing the identification of medications most likely to cause them.
    • Supporting more informed decisions across care transitions.
    • Enabling more efficient medication reconciliation, which reduces patient readmissions.


    More than 40% of medication errors result from inadequate medication reconciliation.16


    More than 770,000 people die or are injured annually from ADEs.17


    23% of patients readmitted within 30 days of discharge had an ADE as either a primary or secondary diagnosis.18


    Surescripts can provide medication history for approximately 66% (two-thirds) of the U.S. population.


    improved completeness of medication history

    20 Min.

    savings per patient

    2 Billion+

    Prescription Records

  • EPCS:

    Addressing Controlled Substance Fraud and Abuse

    Controlled substance fraud and abuse is at an all-time high. Since 1995, drug overdoses have tripled and in 2009, there were 1.2 million Emergency Department visits related to substance abuse. Today, between 3% and 9% of drugs that are diverted for abuse are tied to fraud and forgery of paper prescriptions.19 The electronic prescribing of controlled substances can help combat this epidemic by replacing the fraud-prone paper prescription pad. The Drug Enforcement Administration found that e-prescribing could yield up to $700 million in annual savings.20 Surescripts’ Electronic Prescribing of Controlled Substances (EPCS) provides one electronic workflow for all prescriptions, reduces fraud and abuse, and improves safety by reducing the diversion of controlled substances.

    • EPCS is legal in 47 states and DC.
    • 98% of providers who e-prescribe also prescribe controlled substances.21
    • Controlled substances represent 13% of all prescriptions.22
    • 40% of pharmacies are enabled for EPCS.
    Percent (%) of Pharmacies Enabled for EPCS

  • Immunization Services:

    Driving More Coordinated Care

    Over the past 50 years, the growth and effectiveness of vaccines have helped reduce preventable diseases such as polio, measles and rubella by 99% according to the CDC. Today, care providers are looking to utilize immunizations to address more adaptable viral diseases, like influenza, that require serial vaccinations. Yet, in 2013, only 41.5% of the U.S. population received the influenza vaccination.23

    Pharmacies and retail clinics are playing an increasingly important role in immunizations. Today, nearly 45% of all adult influenza vaccinations occur in pharmacies and retail clinics.23

    Surescripts offers two Immunization Services to help improve the coordination of care.

    • Immunization Notifications provide physicians a more complete view of a patient’s medical history, so they can ensure the best course of treatment.
    • Immunization Registry Reporting simplifies the process of providing immunization information to mandatory and voluntary state and regional registries, allowing pharmacies to save time and other resources.
    Surescripts Connects to 43 Immunization Registries

    Surescripts connects to 43 immunization registries nationwide, covering more than 246 million individuals (80% of the U.S. population in 2010).

  • image 2013 Safe-rx State Rankings

    Safe-Rx Rankings measure each state’s progress in advancing healthcare safety, efficiency and quality through the adoption and use of e-prescribing. The rankings recognize the full utilization of e-prescribing based on volume of use of Surescripts’ Prescription Benefit, Medication History and Prescription Routing services.

    TOP 10 STATES for E-Prescribing Adoption and Use

    • 1. Delaware
    • 2. Minnesota
    • 3. Vermont
    • 4. Wisconsin
    • 5. Massachusetts
    • 6. North Dakota
    • 7. Connecticut
    • 8. North Carolina
    • 9. New Hampshire
    • 10. South Dakota
  • image 2013 Safe-rx State Rankings


Delaware has ranked in the top 5 since
the Safe-Rx rankings began in 2007.



Surescripts Today

Our purpose is to connect fragmented healthcare into a coherent whole to enable more efficient and effective healthcare. Each day, our work touches upon a wide range of people, processes and products rooted in our three core capabilities:


We connect to the broadest community of care partners. Surescripts helps improve care collaboration, saving time and resources, by integrating disparate IT systems between hospitals, physicians, payers, pharmacies, labs and other healthcare stakeholders.


We exchange a wide range of information across networks from a single point of connectivity, facilitating timely and secure access to the data that is needed in today’s quality-driven and evidenced-based care environment.


We activate data so it becomes useful information, while ensuring data security and privacy. We aggregate and enhance data from disparate sources and across different formats.

The Evolution of Surescripts

Surescripts Progress


Industry Progress


SureScripts founded

4% of office-based physicians e-prescribed

E-prescribing legalized in all 50 states and D.C.
SureScripts and RxHub merged
DEA proposed Electronic Prescribing of Controlled Substances (EPCS) rule
SureScripts-RxHub relaunched as Surescripts
  • American Recovery and Reinvestment Act provided $19 billion to drive health IT adoption
  • CMS released Meaningful Use regulations
  • Medicare launched MIPPA e-prescribing incentive program
Clinical Messaging and EPCS launched
36% of office-based physicians e-prescribed

  • 58% of office-based physicians e-prescribed
  • Meaningful Use Stage 1 initiated
Prescription Drug Monitoring Program (PDMP) and Immunization Notifications launched
69% of office-based physicians e-prescribed
  • 58% of eligible prescriptions routed electronically
  • Electronic Prior Authorization, Medication History and Immunization Registry Reporting launched
  • 73% of office-based physicians e-prescribed
  • EPCS legalized in 48 states

Surescripts Progress

Industry Progress

SureScripts founded
4% of office-based physicians e-prescribed
E-prescribing legalized in all 50 states and D.C.
SureScripts and RxHub merged
DEA proposed Electronic Prescribing of Controlled Substances (EPCS) rule
SureScripts-RxHub relaunched as Surescripts
SureScripts-RxHub relaunched as Surescripts

1 - Based on a total count of 522,000 office-based physicians in the U.S. per SK&A data. Surescripts’ count of active-physician responses represents those ambulatory-care physicians who used electronic prescription routing within the last 30 days of 2013. For the calculation of active office-based physicians in 2013, Surescripts made a 15% adjustment to remove acute physicians that are e-prescribing.

2 - Electronic prescriptions of controlled substances are not included.

3 - Surescripts’ analysis of American Hospital Association data and U.S. Census Live Tracker Data.

4 - American Hospital Association. Fast Facts on U.S. Hospitals. Available here.

5 - Source. Accessed 3/10/2014 at 11:12am et.

6 - Surescripts’ analysis of NHAMCS data: National Hospital Ambulatory Medical Care Survey: 2010 Emergency Department Summary Tables, tables 1, 4, 14, 24. Available here.

7 - Surescripts’ analysis of American Hospital Association data.

8 - Surescripts’ analysis of ‘CMS Medicare and Medicaid EHR Incentive Program, electronic health record products used for attestation.’ Data available here.

9 - Surescripts’ analysis of National Council for Prescription Drug Plan pharmacy data.

10 - Surescripts’ analysis of ‘Total Number of Retail Prescription Drugs Filled at Pharmacies.’ Kaiser Family Foundation. Available here.

11 - Surescripts’ estimate.

12 - Surescripts’ analysis of SK&A data.

13 - Surescripts’ analysis of National Ambulatory Medical Survey: 2010 Summary Tables. Available here.

14 - Ibid.

15 - Surescripts’ analysis of Laboratory Corporation of America Holdings. Form 10-K, December 31, 2013.

16 - Rozich JD, Howard RJ, Justeson JM, et al. Patient safety standardization as a mechanism to improve safety in healthcare. Jt. Comm J Qual Saf 2004: 30(1):5–14.

17 - The Agency for Healthcare Research and Quality (AHRQ).

18 - FormularyWatch.

19 - Butler SF, Budman SH, Licari A, et al. National addictions vigilance intervention and prevention program (NAVIPPRO): a real-time, product-specific, public health surveillance system for monitoring prescription drug abuse. Pharmacoepidemiol Drug Saf 2008;17:1142–54. ALSO, Rosenblum A, Parrino M, Schnoll SH, et al. Prescription opioid abuse among enrollees into ­methadone maintenance treatment. Drug Alcohol Depend 2007; 90:64–71.

20 - DEA, U.S. Department of Justice, Economic Impact Analysis of the Interim Final Prescription Rule, March 2010.

21 - 2010 Surescripts survey of 1,375 providers who e-prescribed.

22 - National Association of Chain Drug Stores (NACDS 2013).

23 - U.S. Centers for Disease Control & Prevention.